Foundational characteristics of cancer include proliferation, angiogenesis, migration, evasion of apoptosis, and cellular immortality. Find key markers for these cellular processes and antibodies to detect them.
The SUMOplot™ Analysis Program predicts and scores sumoylation sites in your protein. SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle.
The Autophagy Receptor Motif Plotter predicts and scores autophagy receptor binding sites in your protein. Identifying proteins connected to this pathway is critical to understanding the role of autophagy in physiological as well as pathological processes such as development, differentiation, neurodegenerative diseases, stress, infection, and cancer.
FITC Anti-Mouse CD2 (RM2-5) Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| FC |
|---|---|
| Isotype | Rat IgG2b, lambda |
| Concentration | 0.5 mg/mL |
| Reactivity | Mouse |
| Formulation | 10 mM NaH2PO4, 150 mM NaCl, 0.09% NaN3, 0.1% gelatin, pH7.2 |
| Host | Rat |
| Gene ID | 12481 |
|---|---|
| Gene Name | Cd2 |
| Alternative Name(s) | LFA-2, Ly-37 |
| Format | FITC |
| Preparation | This monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation. It is recommended to store the product undiluted at 4°C, and protected from prolonged exposure to light. Do not freeze. |
| Application Notes | This antibody preparation has been quality-tested for flow cytometry using mouse spleen cells, or an appropriate cell type (where indicated). The amount of antibody required for optimal staining of a cell sample should be determined empirically in your system. |
| Storage Conditions | 2-8°C protected from light |
Yagita H, Nakamura T, Karasuyama H, Okumura K. 1989. Proc. Natl. Acad. Sci. 86(2):645-9.
Nakamura T, Takahashi K, Fukazawa T, Koyanagi M, Yokoyama A, Kato H, Yagita H, Okumura K. 1990. J. Immunol. 145(11):3628-34.
Criado G, Feito MJ, Rojo JM. 1996. Eur. J. Immunol. 26(6):1228-34.
Cibotti R, Punt JA, Dash KS, Sharrow SO, Singer A. 1997. Immunity. 6(3):245-55.
Provided below are standard protocols that you may find useful for product applications.
Background
The RM2-5 antibody reacts with mouse CD2, an approximately 50 kDa glycoprotein, and a member of the Ig superfamily. CD2, also known as LFA-2, is a receptor for CD48 in the mouse and is expressed on the cell surface of all mouse lymphocytes. CD2 mediates adhesion between cells and is involved in T cell activation.RM2-5 is reported to block CD2-mediated cell:cell adhesion.
References
Yagita H, Nakamura T, Karasuyama H, Okumura K. 1989. Proc. Natl. Acad. Sci. 86(2):645-9. Nakamura T, Takahashi K, Fukazawa T, Koyanagi M, Yokoyama A, Kato H, Yagita H, Okumura K. 1990. J. Immunol. 145(11):3628-34. Criado G, Feito MJ, Rojo JM. 1996. Eur. J. Immunol. 26(6):1228-34. Cibotti R, Punt JA, Dash KS, Sharrow SO, Singer A. 1997. Immunity. 6(3):245-55.
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.
Ordering Information
Other Products
Shipping Information
