UNC5B Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant UNC5B.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q8IZJ1 |
Other Accession | NM_170744 |
Reactivity | Human |
Host | mouse |
Clonality | Monoclonal |
Isotype | IgG1 kappa |
Clone Names | 1A9 |
Calculated MW | 103638 Da |
Gene ID | 219699 |
---|---|
Other Names | Netrin receptor UNC5B, Protein unc-5 homolog 2, Protein unc-5 homolog B, p53-regulated receptor for death and life protein 1, UNC5B, P53RDL1, UNC5H2 |
Target/Specificity | UNC5B (NP_734465, 27 a.a. ~ 126 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
Dilution | WB~~1:500~1000 |
Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
Precautions | UNC5B Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
UNC5B belongs to a family of netrin-1 (MIM 601614) receptors thought to mediate the chemorepulsive effect of netrin-1 on specific axons. For more information on UNC5 proteins, see UNC5C (MIM 603610).
References
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.Characterization and expression of netrin-1 and its receptors UNC5B and DCC in human placenta. Dakouane-Giudicelli M, et al. J Histochem Cytochem, 2010 Jan. PMID 19826074.Role of the netrin system of repellent factors on synovial fibroblasts in rheumatoid arthritis and osteoarthritis. Schubert T, et al. Int J Immunopathol Pharmacol, 2009 Jul-Sep. PMID 19822088.Unc5B associates with LARG to mediate the action of repulsive guidance molecule. Hata K, et al. J Cell Biol, 2009 Mar 9. PMID 19273616.Molecular genetics of adult ADHD: converging evidence from genome-wide association and extended pedigree linkage studies. Lesch KP, et al. J Neural Transm, 2008 Nov. PMID 18839057.
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.