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UBE2D2 Antibody (monoclonal) (M02)

Mouse monoclonal antibody raised against a partial recombinant UBE2D2.

     
  • WB - UBE2D2 Antibody (monoclonal) (M02) AT4432a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.08 KDa) .
    detail
  • WB - UBE2D2 Antibody (monoclonal) (M02) AT4432a
    UBE2D2 monoclonal antibody (M02), clone 4A1. Western Blot analysis of UBE2D2 expression in PC-12 ( (Cat # AT4432a )
    detail
  • WB - UBE2D2 Antibody (monoclonal) (M02) AT4432a
    UBE2D2 monoclonal antibody (M02), clone 4A1. Western Blot analysis of UBE2D2 expression in Raw 264.7 ( (Cat # AT4432a )
    detail
  • WB - UBE2D2 Antibody (monoclonal) (M02) AT4432a
    UBE2D2 monoclonal antibody (M02), clone 4A1 Western Blot analysis of UBE2D2 expression in NIH/3T3 ( (Cat # AT4432a )
    detail
  • IHC - UBE2D2 Antibody (monoclonal) (M02) AT4432a
    Immunoperoxidase of monoclonal antibody to UBE2D2 on formalin-fixed paraffin-embedded human small Intestine. [antibody concentration 3 ug/ml]
    detail
  • E - UBE2D2 Antibody (monoclonal) (M02) AT4432a
    Detection limit for recombinant GST tagged UBE2D2 is approximately 3ng/ml as a capture antibody.
    detail
  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IHC, E
Primary Accession P62837
Other Accession NM_003339
Reactivity Human, Mouse, Rat
Host Mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 4A1
Calculated MW 16735 Da
Additional Information
Gene ID 7322
Other Names Ubiquitin-conjugating enzyme E2 D2, Ubiquitin carrier protein D2, Ubiquitin-conjugating enzyme E2(17)KB 2, Ubiquitin-conjugating enzyme E2-17 kDa 2, Ubiquitin-protein ligase D2, p53-regulated ubiquitin-conjugating enzyme 1, UBE2D2, PUBC1, UBC4, UBC5B, UBCH4, UBCH5B
Target/Specificity UBE2D2 (NP_003330, 1 a.a. ~ 94 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsUBE2D2 Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)
citation

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Background

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Two alternatively spliced transcript variants have been found for this gene and they encode distinct isoforms.

References

1.A 4-gene signature predicts survival of patients with resected adenocarcinoma of the esophagus, junction, and gastric cardia.Peters CJ, Rees JR, Hardwick RH, Hardwick JS, Vowler SL, Ong CA, Zhang C, Save V, O'Donovan M, Rassl D, Alderson D, Caldas C, Fitzgerald RC, OCCAMS Study Group.Gastroenterology (2009), doi: 10.1053/ j.gastro.2010.05.080.

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$ 350.00
Cat# AT4432a
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Availability: 7-10 days
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