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TNFRSF6B Antibody (monoclonal) (M02)

Mouse monoclonal antibody raised against a partial recombinant TNFRSF6B.

     
  • WB - TNFRSF6B Antibody (monoclonal) (M02) AT4281a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (37.84 KDa) .
    detail
  • IHC - TNFRSF6B Antibody (monoclonal) (M02) AT4281a
    Immunoperoxidase of monoclonal antibody to TNFRSF6B on formalin-fixed paraffin-embedded human tonsil. [antibody concentration 3 ug/ml]
    detail
  • E - TNFRSF6B Antibody (monoclonal) (M02) AT4281a
    Detection limit for recombinant GST tagged TNFRSF6B is approximately 0.1ng/ml as a capture antibody.
    detail
  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IHC, E
Primary Accession O95407
Other Accession NM_032945
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 7G5
Calculated MW 32680 Da
Additional Information
Gene ID 8771
Other Names Tumor necrosis factor receptor superfamily member 6B, Decoy receptor 3, DcR3, Decoy receptor for Fas ligand, M68, TNFRSF6B, DCR3, TR6
Target/Specificity TNFRSF6B (NP_116563, 32 a.a. ~ 141 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsTNFRSF6B Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)
citation

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Background

This gene belongs to the tumor necrosis factor receptor superfamily. The encoded protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death. It acts as a decoy receptor that competes with death receptors for ligand binding. Overexpression of this gene has been noted in gastrointestinal tract tumors, and it is located in a gene-rich cluster on chromosome 20, with other potentially tumor-related genes. Two transcript variants encoding the same isoform, but differing in the 5' UTR, have been observed for this gene.

References

1.EGFR-driven up-regulation of decoy receptor 3 in keratinocytes contributes to the pathogenesis of psoriasis.Wu NL, Huang DY, Hsieh SL, Hsiao CH, Lee TA, Lin WWBiochim Biophys Acta. 2013 May 23. pii: S0925-4439(13)00182-8. doi: 10.1016/j.bbadis.2013.05.020.

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$ 350.00
Cat# AT4281a
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Availability: 7-10 days
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