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SGTA Antibody (monoclonal) (M06)
Mouse monoclonal antibody raised against a partial recombinant SGTA.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IF, IP, E |
|---|---|
| Primary Accession | O43765 |
| Other Accession | NM_003021 |
| Reactivity | Human |
| Host | mouse |
| Clonality | Monoclonal |
| Isotype | IgG2b Kappa |
| Clone Names | 2E12 |
| Calculated MW | 34063 Da |
| Gene ID | 6449 |
|---|---|
| Other Names | Small glutamine-rich tetratricopeptide repeat-containing protein alpha, Alpha-SGT, Vpu-binding protein, UBP, SGTA, SGT, SGT1 |
| Target/Specificity | SGTA (NP_003012.1, 42 a.a. ~ 123 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | SGTA Antibody (monoclonal) (M06) is for research use only and not for use in diagnostic or therapeutic procedures. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a protein which is capable of interacting with the major nonstructural protein of parvovirus H-1 and 70-kDa heat shock cognate protein; however, its function is not known. Since this transcript is expressed ubiquitously in various tissues, this protein may serve a housekeeping function.
References
Family-based analysis of candidate genes for polycystic ovary syndrome. Ewens KG, et al. J Clin Endocrinol Metab, 2010 May. PMID 20200332.Defining the human deubiquitinating enzyme interaction landscape. Sowa ME, et al. Cell, 2009 Jul 23. PMID 19615732.Structural and functional characterization of human SGT and its interaction with Vpu of the human immunodeficiency virus type 1. Dutta S, et al. Biochemistry, 2008 Sep 23. PMID 18759457.Expression, purification and preliminary crystallographic analysis of recombinant human small glutamine-rich tetratricopeptide-repeat protein. Dutta S, et al. Acta Crystallogr Sect F Struct Biol Cryst Commun, 2008 Jul 1. PMID 18607086.Small glutamine-rich tetratricopeptide repeat-containing protein alpha (SGTA), a candidate gene for polycystic ovary syndrome. Goodarzi MO, et al. Hum Reprod, 2008 May. PMID 18332089.
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