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SERPINA6 Antibody (monoclonal) (M04)

Mouse monoclonal antibody raised against a full length recombinant SERPINA6.

     
  • WB - SERPINA6 Antibody (monoclonal) (M04) AT3820a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (67.87 KDa) .
    detail
  • E - SERPINA6 Antibody (monoclonal) (M04) AT3820a
    Detection limit for recombinant GST tagged SERPINA6 is approximately 1ng/ml as a capture antibody.
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P08185
Other Accession BC058021
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG1 Kappa
Clone Names 3B12
Calculated MW 45141 Da
Additional Information
Gene ID 866
Other Names Corticosteroid-binding globulin, CBG, Serpin A6, Transcortin, SERPINA6, CBG
Target/Specificity SERPINA6 (AAH58021, 23 a.a. ~ 405 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsSERPINA6 Antibody (monoclonal) (M04) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)
citation

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Background

This gene encodes an alpha-globulin protein with corticosteroid-binding properties. This is the major transport protein for glucorticoids and progestins in the blood of most vertebrates. The gene localizes to a chromosomal region containing several closely related serine protease inhibitors which may have evolved by duplication events.

References

Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.Genetic variation in neuroendocrine genes associates with somatic symptoms in the general population: results from the EPIFUND study. Holliday KL, et al. J Psychosom Res, 2010 May. PMID 20403506.Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.Plasma sex hormone-binding globulin, corticosteroid-binding globulin, cortisol, and free cortisol levels in outpatients attending a lipid disorders clinic: a cross-sectional study of 1137 subjects. Lewis JG, et al. Horm Metab Res, 2010 Apr. PMID 20354921.Effect of mutations of the human serpin protein corticosteroid-binding globulin on cortisol-binding, thermal and protease sensitivity. Braun BC, et al. J Steroid Biochem Mol Biol, 2010 May. PMID 20226861.

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$ 350.00
Cat# AT3820a
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Availability: 7-10 days
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