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S100A2 Antibody (monoclonal) (M03)

Mouse monoclonal antibody raised against a full length recombinant S100A2.

     
  • IF - S100A2 Antibody (monoclonal) (M03) AT3754a
    Immunofluorescence of monoclonal antibody to S100A2 on A-431 cell. [antibody concentration 15 ug/ml]
    detail
  • WB - S100A2 Antibody (monoclonal) (M03) AT3754a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.41 KDa) .
    detail
  • WB - S100A2 Antibody (monoclonal) (M03) AT3754a
    S100A2 monoclonal antibody (M03), clone 3H8 Western Blot analysis of S100A2 expression in A-431 ( (Cat # AT3754a )
    detail
  • WB - S100A2 Antibody (monoclonal) (M03) AT3754a
    Western Blot analysis of S100A2 expression in transfected 293T cell line by S100A2 monoclonal antibody (M03), clone 3H8.

    Lane 1: S100A2 transfected lysate(11 KDa).
    Lane 2: Non-transfected lysate.
    detail
  • E - S100A2 Antibody (monoclonal) (M03) AT3754a
    Detection limit for recombinant GST tagged S100A2 is 0.3 ng/ml as a capture antibody.
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IF, E
Primary Accession P29034
Other Accession BC002829
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2b Kappa
Clone Names 3H8
Calculated MW 11117 Da
Additional Information
Gene ID 6273
Other Names Protein S100-A2, CAN19, Protein S-100L, S100 calcium-binding protein A2, S100A2, S100L
Target/Specificity S100A2 (AAH02829, 1 a.a. ~ 97 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsS100A2 Antibody (monoclonal) (M03) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)
citation

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Background

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may have a tumor suppressor function. Chromosomal rearrangements and altered expression of this gene have been implicated in breast cancer.

References

An approach based on a genome-wide association study reveals candidate loci for narcolepsy. Shimada M, et al. Hum Genet, 2010 Oct. PMID 20677014.S100 proteins interact with the N-terminal domain of MDM2. van Dieck J, et al. FEBS Lett, 2010 Aug 4. PMID 20591429.Expression and clinical significance of S100A2 and p63 in esophageal carcinoma. Cao LY, et al. World J Gastroenterol, 2009 Sep 7. PMID 19725154.Variation in genes of the epidermal differentiation complex in German atopic dermatitis patients. Stemmler S, et al. Int J Immunogenet, 2009 Aug. PMID 19601998.Expression of S100A2 calcium-binding protein predicts response to pancreatectomy for pancreatic cancer. Biankin AV, et al. Gastroenterology, 2009 Aug. PMID 19376121.

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$ 350.00
Cat# AT3754a
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Availability: 7-10 days
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