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RRAS2 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a full length recombinant RRAS2.

     
  • IF - RRAS2 Antibody (monoclonal) (M01) AT3728a
    Immunofluorescence of monoclonal antibody to RRAS2 on A-431 cell. [antibody concentration 10 ug/ml]
    detail
  • WB - RRAS2 Antibody (monoclonal) (M01) AT3728a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (48.18 KDa) .
    detail
  • WB - RRAS2 Antibody (monoclonal) (M01) AT3728a
    RRAS2 monoclonal antibody (M01), clone 2D3-4B8. Western Blot analysis of RRAS2 expression in HeLa ( (Cat # AT3728a )
    detail
  • WB - RRAS2 Antibody (monoclonal) (M01) AT3728a
    RRAS2 monoclonal antibody (M01), clone 2D3-4B8. Western Blot analysis of RRAS2 expression in PC-12((Cat # AT3728a )
    detail
  • WB - RRAS2 Antibody (monoclonal) (M01) AT3728a
    RRAS2 monoclonal antibody (M01), clone 2D3-4B8. Western Blot analysis of RRAS2 expression in Raw 264.7((Cat # AT3728a )
    detail
  • WB - RRAS2 Antibody (monoclonal) (M01) AT3728a
    RRAS2 monoclonal antibody (M01), clone 2D3-4B8 Western Blot analysis of RRAS2 expression in A-431 ( (Cat # AT3728a )
    detail
  • WB - RRAS2 Antibody (monoclonal) (M01) AT3728a
    RRAS2 monoclonal antibody (M01), clone 2D3-4B8. Western Blot analysis of RRAS2 expression in NIH/3T3((Cat # AT3728a )
    detail
  • WB - RRAS2 Antibody (monoclonal) (M01) AT3728a
    Western Blot analysis of RRAS2 expression in transfected 293T cell line by RRAS2 monoclonal antibody (M01), clone 2D3-4B8.

    Lane 1: RRAS2 transfected lysate (Predicted MW: 23.4 KDa).
    Lane 2: Non-transfected lysate.
    detail
  • IHC - RRAS2 Antibody (monoclonal) (M01) AT3728a
    Immunoperoxidase of monoclonal antibody to RRAS2 on formalin-fixed paraffin-embedded human dysgerminoma tissue. [antibody concentration 5 ug/ml]
    detail
  • E - RRAS2 Antibody (monoclonal) (M01) AT3728a
    Detection limit for recombinant GST tagged RRAS2 is 1 ng/ml as a capture antibody.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IHC, IF, E
Primary Accession P62070
Other Accession BC013106
Reactivity Human, Mouse, Rat
Host mouse
Clonality Monoclonal
Isotype IgG1 Kappa
Clone Names 2D3-4B8
Calculated MW 23400 Da
Additional Information
Gene ID 22800
Other Names Ras-related protein R-Ras2, Ras-like protein TC21, Teratocarcinoma oncogene, RRAS2, TC21
Target/Specificity RRAS2 (AAH13106, 1 a.a. ~ 204 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsRRAS2 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)
citation

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Background

This gene encodes a member of the R-Ras subfamily of Ras-like small GTPases. The encoded protein associates with the plasma membrane and may function as a signal transducer. This protein may play an important role in activating signal transduction pathways that control cell proliferation. Mutations in this gene are associated with the growth of certain tumors. Pseudogenes of this gene are found on chromosomes 1 and 2. Alternate splicing results in multiple transcript variants.

References

1.In Vivo Regulation of TGF-?] by R-Ras2 Revealed through Loss of the RasGAP Protein NF1.Patmore DM, Welch S, Fulkerson PC, Wu J, Choi K, Eaves D, Kordich JJ, Collins MH, Cripe TP, Ratner N.Cancer Res. 2012 Oct 15;72(20):5317-27. doi: 10.1158/0008- 5472.CAN-12-1972. Epub 2012 Aug 23.

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$ 350.00
Cat# AT3728a
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Availability: 7-10 days
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