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RHOJ Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a full length recombinant RHOJ.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IF, E |
|---|---|
| Primary Accession | Q9H4E5 |
| Other Accession | BC062575 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 lambda |
| Clone Names | 1E5 |
| Calculated MW | 23821 Da |
| Gene ID | 57381 |
|---|---|
| Other Names | Rho-related GTP-binding protein RhoJ, Ras-like protein family member 7B, Tc10-like GTP-binding protein, RHOJ, ARHJ, RASL7B, RHOI, TCL |
| Target/Specificity | RHOJ (AAH62575, 1 a.a. ~ 214 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | RHOJ Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
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Provided below are standard protocols that you may find useful for product applications.
Background
ARHJ belongs to the Rho family of small GTP-binding proteins. Rho proteins regulate the dynamic assembly of cytoskeletal components for several physiologic processes, such as cell proliferation and motility and the establishment of cell polarity. They are also involved in pathophysiologic process, such as cell transformation and metastasis.
References
1.RhoJ and Pak Kinases Regulate Melanoma Chemoresistance by Suppressing Pathways that Sense DNA Damage.Ho H, Aruri J, Kapadia R, Mehr H, White MA, Ganesan AK.Cancer Res. 2012 Sep 12. [Epub ahead of print]2.Sema3E-PlexinD1 signaling selectively suppresses disoriented angiogenesis in ischemic retinopathy in mice.Fukushima Y, Okada M, Kataoka H, Hirashima M, Yoshida Y, Mann F, Gomi F, Nishida K, Nishikawa S, Uemura A.J Clin Invest. 2011 May 2;121(5):1974-85. doi: 10.1172/JCI44900. Epub 2011 Apr 18.
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