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PROCR Antibody (monoclonal) (M03)

Mouse monoclonal antibody raised against a full length recombinant PROCR.

     
  • IF - PROCR Antibody (monoclonal) (M03) AT3440a
    Immunofluorescence of monoclonal antibody to PROCR on HeLa cell. [antibody concentration 10 ug/ml]
    detail
  • WB - PROCR Antibody (monoclonal) (M03) AT3440a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (51.92 KDa) .
    detail
  • IHC - PROCR Antibody (monoclonal) (M03) AT3440a
    Immunoperoxidase of monoclonal antibody to PROCR on formalin-fixed paraffin-embedded human malignant lymphoma, diffuse large B tissue. [antibody concentration 3 ug/ml]
    detail
  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IHC, IF
Primary Accession Q9UNN8
Other Accession BC014451
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1 Kappa
Clone Names M2
Calculated MW 26671 Da
Additional Information
Gene ID 10544
Other Names Endothelial protein C receptor, Activated protein C receptor, APC receptor, Endothelial cell protein C receptor, CD201, PROCR, EPCR
Target/Specificity PROCR (AAH14451.1, 1 a.a. ~ 238 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsPROCR Antibody (monoclonal) (M03) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)
citation

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Background

The protein encoded by this gene is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. The encoded protein is an N-glycosylated type I membrane protein that enhances the activation of protein C. Mutations in this gene have been associated with venous thromboembolism and myocardial infarction, as well as with late fetal loss during pregnancy.

References

1.Inhibitory effects of epi-sesamin on endothelial protein C receptor shedding in vitro and in vivo.Ku SK, Lee W, Yoo H, Han CK, Bae JSInflamm Res. 2013 Jul 25.2.Rosmarinic acid down-regulates endothelial protein C receptor shedding in vitro and in vivo.Ku SK, Yang EJ, Song KS, Bae JSFood Chem Toxicol. 2013 Jun 14;59C:311-315. doi: 10.1016/j.fct.2013.06.003.3.Down-regulation of endothelial protein C receptor shedding by persicarin and isorhamnetin-3-O-galactoside.Ku SK, Han MS, Bae JSThromb Res. 2013 May 30. pii: S0049-3848(13)00196-5. doi: 10.1016/j.thromres.2013.05.004.4.Emodin-6-O-?]-D-glucoside down-regulates endothelial protein C receptor shedding.Lee W, Ku SK, Bae JSArch Pharm Res. 2013 Apr 16.

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$ 350.00
Cat# AT3440a
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Availability: 7-10 days
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