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>   home   >   Products   >   Primary Antibodies   >   NR1D2 Antibody (monoclonal) (M01)   

NR1D2 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a full length recombinant NR1D2.

     
  • IF - NR1D2 Antibody (monoclonal) (M01) AT3095a
    Immunofluorescence of monoclonal antibody to NR1D2 on HeLa cell. [antibody concentration 10 ug/ml]
    detail
  • WB - NR1D2 Antibody (monoclonal) (M01) AT3095a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (89.21 KDa) .
    detail
  • WB - NR1D2 Antibody (monoclonal) (M01) AT3095a
    NR1D2 monoclonal antibody (M01), clone 1G2 Western Blot analysis of NR1D2 expression in Hela ( (Cat # AT3095a )
    detail
  • WB - NR1D2 Antibody (monoclonal) (M01) AT3095a
    Western Blot analysis of NR1D2 expression in transfected 293T cell line by NR1D2 monoclonal antibody (M01), clone 1G2.

    Lane 1: NR1D2 transfected lysate(64.7 KDa).
    Lane 2: Non-transfected lysate.
    detail
  • E - NR1D2 Antibody (monoclonal) (M01) AT3095a
    Detection limit for recombinant GST tagged NR1D2 is approximately 0.03ng/ml as a capture antibody.
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IF
Primary Accession Q14995
Other Accession BC045613
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG1 kappa
Clone Names 1G2
Calculated MW 64643 Da
Additional Information
Gene ID 9975
Other Names Nuclear receptor subfamily 1 group D member 2, Orphan nuclear hormone receptor BD73, Rev-erb alpha-related receptor, RVR, Rev-erb-beta, V-erbA-related protein 1-related, EAR-1R, NR1D2
Target/Specificity NR1D2 (AAH45613, 1 a.a. ~ 579 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsNR1D2 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Citations (0)
citation

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Background

This gene encodes a member of the nuclear hormone receptor family, specifically the NR1 subfamily of receptors. The encoded protein functions as a transcriptional repressor and may play a role in circadian rhythms and carbohydrate and lipid metabolism. Alternatively spliced transcript variants have been described.

References

Nuclear receptor rev-erb-{alpha} circadian gene variants and lithium carbonate prophylaxis in bipolar affective disorder. Campos-de-Sousa S, et al. J Biol Rhythms, 2010 Apr. PMID 20348464.Redundant function of REV-ERBalpha and beta and non-essential role for Bmal1 cycling in transcriptional regulation of intracellular circadian rhythms. Liu AC, et al. PLoS Genet, 2008 Feb 29. PMID 18454201.Nuclear hormone receptors for heme: REV-ERBalpha and REV-ERBbeta are ligand-regulated components of the mammalian clock. Burris TP. Mol Endocrinol, 2008 Jul. PMID 18218725.Identification of heme as the ligand for the orphan nuclear receptors REV-ERBalpha and REV-ERBbeta. Raghuram S, et al. Nat Struct Mol Biol, 2007 Dec. PMID 18037887.The orphan nuclear receptor Rev-erbbeta recruits Tip60 and HDAC1 to regulate apolipoprotein CIII promoter. Wang J, et al. Biochim Biophys Acta, 2008 Feb. PMID 17996965.

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$ 350.00
Cat# AT3095a
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Availability: 7-10 days
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