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NOVA1 Antibody (monoclonal) (M10)
Mouse monoclonal antibody raised against a partial recombinant NOVA1.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | P51513 |
| Other Accession | NM_002515 |
| Reactivity | Human, Rat |
| Host | mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 Kappa |
| Clone Names | 5D9 |
| Calculated MW | 51727 Da |
| Gene ID | 4857 |
|---|---|
| Other Names | RNA-binding protein Nova-1, Neuro-oncological ventral antigen 1, Onconeural ventral antigen 1, Paraneoplastic Ri antigen, Ventral neuron-specific protein 1, NOVA1 |
| Target/Specificity | NOVA1 (NP_002506, 408 a.a. ~ 507 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | NOVA1 Antibody (monoclonal) (M10) is for research use only and not for use in diagnostic or therapeutic procedures. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a neuron-specific RNA-binding protein, a member of the Nova family of paraneoplastic disease antigens, that is recognized and inhibited by paraneoplastic antibodies. These antibodies are found in the sera of patients with paraneoplastic opsoclonus-ataxia, breast cancer, and small cell lung cancer. Alternatively spliced transcripts encoding distinct isoforms have been described.
References
Genome-wide association study of antipsychotic-induced parkinsonism severity among schizophrenia patients. Alkelai A, et al. Psychopharmacology (Berl), 2009 Oct. PMID 19680635.Genetic variants associated with cardiac structure and function: a meta-analysis and replication of genome-wide association data. Vasan RS, et al. JAMA, 2009 Jul 8. PMID 19584346.Conduct disorder and ADHD: evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study. Anney RJ, et al. Am J Med Genet B Neuropsychiatr Genet, 2008 Dec 5. PMID 18951430.Paraneoplastic antibody during follow-up of a patient with anti-Ri-associated paraneoplastic neurological syndrome. Stich O, et al. Acta Neurol Scand, 2009 May. PMID 18822086.Post-transcriptional regulation of neuro-oncological ventral antigen 1 by the neuronal RNA-binding proteins ELAV. Ratti A, et al. J Biol Chem, 2008 Mar 21. PMID 18218628.
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