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NNT Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a full length recombinant NNT.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IF, E |
|---|---|
| Primary Accession | Q13423 |
| Other Accession | BC032370 |
| Reactivity | Human |
| Host | mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 kappa |
| Clone Names | 1D6 |
| Calculated MW | 113896 Da |
| Gene ID | 23530 |
|---|---|
| Other Names | NAD(P) transhydrogenase, mitochondrial, Nicotinamide nucleotide transhydrogenase, Pyridine nucleotide transhydrogenase, NNT |
| Target/Specificity | NNT (AAH32370, 1 a.a. ~ 207 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | NNT Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes an integral protein of the inner mitochondrial membrane. The enzyme couples hydride transfer between NAD(H) and NADP(+) to proton translocation across the inner mitochondrial membrane. Under most physiological conditions, the enzyme uses energy from the mitochondrial proton gradient to produce high concentrations of NADPH. The resulting NADPH is used for biosynthesis and in free radical detoxification. Two alternatively spliced variants, encoding the same protein, have been found for this gene.
References
1.Ethanol intoxication increases hepatic N-lysyl protein acetylation.Picklo MJ Sr.Biochem Biophys Res Commun. 2008 Nov 21;376(3):615-9. Epub 2008 Sep 18.
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