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MSI1 Antibody (monoclonal) (M05)

Mouse monoclonal antibody raised against a full length recombinant MSI1.

     
  • IF - MSI1 Antibody (monoclonal) (M05) AT2914a
    Immunofluorescence of monoclonal antibody to MSI1 on HeLa cell . [antibody concentration 10 ug/ml]
    detail
  • WB - MSI1 Antibody (monoclonal) (M05) AT2914a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (35.57 KDa) .
    detail
  • IHC - MSI1 Antibody (monoclonal) (M05) AT2914a
    Immunoperoxidase of monoclonal antibody to MSI1 on formalin-fixed paraffin-embedded human kidney. [antibody concentration 3 ug/ml]
    detail
  • E - MSI1 Antibody (monoclonal) (M05) AT2914a
    Detection limit for recombinant GST tagged MSI1 is approximately 0.3ng/ml as a capture antibody.
    detail
  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IHC, IF, E
Primary Accession O43347
Other Accession NM_002442
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2b Kappa
Clone Names 1B11
Calculated MW 39125 Da
Additional Information
Gene ID 4440
Other Names RNA-binding protein Musashi homolog 1, Musashi-1, MSI1
Target/Specificity MSI1 (NP_002433, 1 a.a. ~ 87 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsMSI1 Antibody (monoclonal) (M05) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)
citation

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Background

This gene encodes a protein containing two conserved tandem RNA recognition motifs. Similar proteins in other species function as RNA-binding proteins and play central roles in posttranscriptional gene regulation. Expression of this gene has been correlated with the grade of the malignancy and proliferative activity in gliomas and melanomas. A pseudogene for this gene is located on chromosome 11q13.

References

Expression of putative stem cell genes Musashi-1 and beta1-integrin in human colorectal adenomas and adenocarcinomas. Fan LF, et al. Int J Colorectal Dis, 2010 Jan. PMID 19714342.Genomic analyses of musashi1 downstream targets show a strong association with cancer-related processes. de Sousa Abreu R, et al. J Biol Chem, 2009 May 1. PMID 19258308.Musashi-1 suppresses expression of Paneth cell-specific genes in human intestinal epithelial cells. Murayama M, et al. J Gastroenterol, 2009. PMID 19214660.Musashi1 modulates cell proliferation genes in the medulloblastoma cell line Daoy. Sanchez-Diaz PC, et al. BMC Cancer, 2008 Sep 30. PMID 18826648.Increased expression of the adult stem cell marker Musashi-1 in endometriosis and endometrial carcinoma. G?tte M, et al. J Pathol, 2008 Jul. PMID 18473332.

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$ 350.00
Cat# AT2914a
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Availability: 7-10 days
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