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MEOX1 Antibody (monoclonal) (M02)
Mouse monoclonal antibody raised against a partial recombinant MEOX1.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P50221 |
| Other Accession | NM_004527 |
| Reactivity | Human |
| Host | mouse |
| Clonality | Monoclonal |
| Isotype | IgG2a Kappa |
| Clone Names | 1A12 |
| Calculated MW | 27997 Da |
| Gene ID | 4222 |
|---|---|
| Other Names | Homeobox protein MOX-1, Mesenchyme homeobox 1, MEOX1, MOX1 |
| Target/Specificity | MEOX1 (NP_004518.1, 165 a.a. ~ 252 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | MEOX1 Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of a subfamily of non-clustered, diverged, antennapedia-like homeobox-containing genes. The encoded protein may play a role in the molecular signaling network regulating somite development. Alternatively spliced transcript variants encoding different isoforms have been described.
References
Diaphanospondylodysostosis: six new cases and exclusion of the candidate genes, PAX1 and MEOX1. Vatanavicharn N, et al. Am J Med Genet A, 2007 Oct 1. PMID 17764081.The high-mobility-group domain of Sox proteins interacts with DNA-binding domains of many transcription factors. Wissm?ller S, et al. Nucleic Acids Res, 2006. PMID 16582099.Hedgehog signaling induces cardiomyogenesis in P19 cells. Gianakopoulos PJ, et al. J Biol Chem, 2005 Jun 3. PMID 15793308.The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.Disruption of Meox or Gli activity ablates skeletal myogenesis in P19 cells. Petropoulos H, et al. J Biol Chem, 2004 Jun 4. PMID 15039437.
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