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MEIS2 Antibody (monoclonal) (M03)
Mouse monoclonal antibody raised against a full length recombinant MEIS2.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IF |
|---|---|
| Primary Accession | O14770 |
| Other Accession | BC001516 |
| Reactivity | Human |
| Host | mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 Kappa |
| Clone Names | 1D1 |
| Calculated MW | 51790 Da |
| Gene ID | 4212 |
|---|---|
| Other Names | Homeobox protein Meis2, Meis1-related protein 1, MEIS2, MRG1 |
| Target/Specificity | MEIS2 (AAH01516, 1 a.a. ~ 381 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | MEIS2 Antibody (monoclonal) (M03) is for research use only and not for use in diagnostic or therapeutic procedures. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a homeobox protein belonging to the TALE ('three amino acid loop extension') family of homeodomain-containing proteins. TALE homeobox proteins are highly conserved transcription regulators, and several members have been shown to be essential contributors to developmental programs. Multiple transcript variants encoding distinct isoforms have been described for this gene.
References
An autoinhibitory effect of the homothorax domain of Meis2. Hyman-Walsh C, et al. FEBS J, 2010 Jun. PMID 20553494.Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.Genomewide pharmacogenomic study of metabolic side effects to antipsychotic drugs. Adkins DE, et al. Mol Psychiatry, 2010 Mar 2. PMID 20195266.Genetic variants associated with cardiac structure and function: a meta-analysis and replication of genome-wide association data. Vasan RS, et al. JAMA, 2009 Jul 8. PMID 19584346.MEIS proteins as partners of the TLX1/HOX11 oncoprotein. Milech N, et al. Leuk Res, 2010 Mar. PMID 19559479.
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