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MARK2 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant MARK2.

     
  • WB - MARK2 Antibody (monoclonal) (M01) AT2804a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.63 KDa) .
    detail
  • WB - MARK2 Antibody (monoclonal) (M01) AT2804a
    MARK2 monoclonal antibody (M01), clone 3B12. Western Blot analysis of MARK2 expression in PC-12.
    detail
  • WB - MARK2 Antibody (monoclonal) (M01) AT2804a
    MARK2 monoclonal antibody (M01), clone 3B12. Western Blot analysis of MARK2 expression in A-431.
    detail
  • WB - MARK2 Antibody (monoclonal) (M01) AT2804a
    MARK2 monoclonal antibody (M01), clone 3B12. Western Blot analysis of MARK2 expression in NIH/3T3.
    detail
  • E - MARK2 Antibody (monoclonal) (M01) AT2804a
    Detection limit for recombinant GST tagged MARK2 is approximately 0.03ng/ml as a capture antibody.
    detail
  • SPECIFICATION
  • CITATIONS
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  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q7KZI7
Other Accession BC008771
Reactivity Human, Mouse, Rat
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 3B12
Calculated MW 87911 Da
Additional Information
Gene ID 2011
Other Names Serine/threonine-protein kinase MARK2, ELKL motif kinase 1, EMK-1, MAP/microtubule affinity-regulating kinase 2, PAR1 homolog, PAR1 homolog b, Par-1b, Par1b, MARK2 {ECO:0000312|EMBL:AAH087712}, EMK1
Target/Specificity MARK2 (AAH08771, 401 a.a. ~ 500 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsMARK2 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)
citation

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Background

This gene encodes a member of the Par-1 family of serine/threonine protein kinases. The protein is an important regulator of cell polarity in epithelial and neuronal cells, and also controls the stability of microtubules through phosphorylation and inactivation of several microtubule-associating proteins. The protein localizes to cell membranes. Multiple transcript variants encoding different isoforms have been found for this gene.

References

1.Pancreatic LKB1 deletion leads to acinar polarity defects and cystic neoplasms.Hezel AF, Gurumurthy S, Granot Z, Swisa A, Chu GC, Bailey G, Dor Y, Bardeesy N, Depinho RA.Mol Cell Biol. 2008 Apr;28(7):2414-25. Epub 2008 Jan 28.

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$ 350.00
Cat# AT2804a
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