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LASS6 Antibody (monoclonal) (M02)
Mouse monoclonal antibody raised against a partial recombinant LASS6.
- SPECIFICATION
- CITATIONS
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- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q6ZMG9 |
| Other Accession | NM_203463 |
| Reactivity | Human, Rat |
| Host | mouse |
| Clonality | Monoclonal |
| Isotype | IgG2b Kappa |
| Clone Names | 6B8 |
| Calculated MW | 44890 Da |
| Gene ID | 253782 |
|---|---|
| Other Names | Ceramide synthase 6, CerS6, LAG1 longevity assurance homolog 6, CERS6, LASS6 |
| Target/Specificity | LASS6 (NP_982288, 62 a.a. ~ 131 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | LASS6 Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
Ceramide synthases 2, 5, and 6 confer distinct roles in radiation-induced apoptosis in HeLa cells. Mesicek J, et al. Cell Signal, 2010 Sep. PMID 20406683.Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.PERK-dependent regulation of ceramide synthase 6 and thioredoxin play a key role in mda-7/IL-24-induced killing of primary human glioblastoma multiforme cells. Yacoub A, et al. Cancer Res, 2010 Feb 1. PMID 20103619.Increased ceramide synthase 2 and 6 mRNA levels in breast cancer tissues and correlation with sphingosine kinase expression. Erez-Roman R, et al. Biochem Biophys Res Commun, 2010 Jan 1. PMID 19912991.Antiapoptotic roles of ceramide-synthase-6-generated C16-ceramide via selective regulation of the ATF6/CHOP arm of ER-stress-response pathways. Senkal CE, et al. FASEB J, 2010 Jan. PMID 19723703.
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