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KHSRP Antibody (monoclonal) (M09)

Mouse monoclonal antibody raised against a partial recombinant KHSRP.

     
  • IHC - KHSRP Antibody (monoclonal) (M09) AT2609a
    Immunoperoxidase of monoclonal antibody to KHSRP on formalin-fixed paraffin-embedded human esophagus. [antibody concentration 3 ug/ml]
    detail
  • E - KHSRP Antibody (monoclonal) (M09) AT2609a
    Detection limit for recombinant GST tagged KHSRP is approximately 0.3ng/ml as a capture antibody.
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
IHC, E
Primary Accession Q92945
Other Accession NM_003685
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 4H7
Calculated MW 73115 Da
Additional Information
Gene ID 8570
Other Names Far upstream element-binding protein 2, FUSE-binding protein 2, KH type-splicing regulatory protein, KSRP, p75, KHSRP, FUBP2
Target/Specificity KHSRP (NP_003676, 151 a.a. ~ 239 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsKHSRP Antibody (monoclonal) (M09) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)
citation

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Background

The KHSRP gene encodes a multifunctional RNA-binding protein implicated in a variety of cellular processes, including transcription, alternative pre-mRNA splicing, and mRNA localization (Min et al., 1997 [PubMed 9136930]; Gherzi et al., 2004 [PubMed 15175153]).

References

Antagonistic role of hnRNP A1 and KSRP in the regulation of let-7a biogenesis. Michlewski G, et al. Nat Struct Mol Biol, 2010 Aug. PMID 20639884.Dishevelled-KSRP complex regulates Wnt signaling through post-transcriptional stabilization of beta-catenin mRNA. Bikkavilli RK, et al. J Cell Sci, 2010 Apr 15. PMID 20332102.KSRP-PMR1-exosome association determines parathyroid hormone mRNA levels and stability in transfected cells. Nechama M, et al. BMC Cell Biol, 2009 Sep 23. PMID 19775426.Overexpression of far upstream element binding proteins: a mechanism regulating proliferation and migration in liver cancer cells. Malz M, et al. Hepatology, 2009 Oct. PMID 19585652.The RNA-binding protein KSRP promotes the biogenesis of a subset of microRNAs. Trabucchi M, et al. Nature, 2009 Jun 18. PMID 19458619.

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$ 350.00
Cat# AT2609a
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Availability: 7-10 days
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