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KHDRBS1 Antibody (monoclonal) (M03)

Mouse monoclonal antibody raised against a partial recombinant KHDRBS1.

     
  • IF - KHDRBS1 Antibody (monoclonal) (M03) AT2607a
    Immunofluorescence of monoclonal antibody to KHDRBS1 on A-431 cell. [antibody concentration 10 ug/ml]
    detail
  • WB - KHDRBS1 Antibody (monoclonal) (M03) AT2607a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.63 KDa) .
    detail
  • WB - KHDRBS1 Antibody (monoclonal) (M03) AT2607a
    KHDRBS1 monoclonal antibody (M03), clone 1A4 Western Blot analysis of KHDRBS1 expression in A-431 ( (Cat # AT2607a )
    detail
  • WB - KHDRBS1 Antibody (monoclonal) (M03) AT2607a
    Western Blot analysis of KHDRBS1 expression in transfected 293T cell line by KHDRBS1 monoclonal antibody (M03), clone 1A4.

    Lane 1: KHDRBS1 transfected lysate(41 KDa).
    Lane 2: Non-transfected lysate.
    detail
  • IHC - KHDRBS1 Antibody (monoclonal) (M03) AT2607a
    Immunoperoxidase of monoclonal antibody to KHDRBS1 on formalin-fixed paraffin-embedded human liver. [antibody concentration 3 ug/ml]
    detail
  • E - KHDRBS1 Antibody (monoclonal) (M03) AT2607a
    Detection limit for recombinant GST tagged KHDRBS1 is approximately 0.03ng/ml as a capture antibody.
    detail
  • SPECIFICATION
  • CITATIONS
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  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IHC, IF, E
Primary Accession Q07666
Other Accession BC000717
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 1A4
Calculated MW 48227 Da
Additional Information
Gene ID 10657
Other Names KH domain-containing, RNA-binding, signal transduction-associated protein 1, GAP-associated tyrosine phosphoprotein p62, Src-associated in mitosis 68 kDa protein, Sam68, p21 Ras GTPase-activating protein-associated p62, p68, KHDRBS1 (HGNC:18116)
Target/Specificity KHDRBS1 (AAH00717, 176 a.a. ~ 275 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsKHDRBS1 Antibody (monoclonal) (M03) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)
citation

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References

The splicing regulator Sam68 binds to a novel exonic splicing silencer and functions in SMN2 alternative splicing in spinal muscular atrophy. Pedrotti S, et al. EMBO J, 2010 Apr 7. PMID 20186123.Sam68 sequestration and partial loss of function are associated with splicing alterations in FXTAS patients. Sellier C, et al. EMBO J, 2010 Apr 7. PMID 20186122.Alternative splicing of the cyclin D1 proto-oncogene is regulated by the RNA-binding protein Sam68. Paronetto MP, et al. Cancer Res, 2010 Jan 1. PMID 20028857.Proteomic identification of heterogeneous nuclear ribonucleoprotein L as a novel component of SLM/Sam68 Nuclear Bodies. Rajan P, et al. BMC Cell Biol, 2009 Nov 13. PMID 19912651.Expression and cytoplasmic localization of SAM68 is a significant and independent prognostic marker for renal cell carcinoma. Zhang Z, et al. Cancer Epidemiol Biomarkers Prev, 2009 Oct. PMID 19755649.

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$ 350.00
Cat# AT2607a
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Availability: 7-10 days
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