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HDAC7A Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a full length recombinant HDAC7A.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q8WUI4 |
| Other Accession | BC006453 |
| Reactivity | Human |
| Host | mouse |
| Clonality | Monoclonal |
| Isotype | IgG2b Kappa |
| Clone Names | 2B11-1C1 |
| Calculated MW | 102927 Da |
| Gene ID | 51564 |
|---|---|
| Other Names | Histone deacetylase 7, HD7, Histone deacetylase 7A, HD7a, HDAC7, HDAC7A |
| Target/Specificity | HDAC7A (AAH06453.1, 1 a.a. ~ 276 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | HDAC7A Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
References
1.HDAC7 and FoxA1 in estrogen-mediated repression of RPRM.Malik S, Jiang S, Garee JP, Verdin E, Lee AV, OMalley BW, Zhang M, Belaguli NS, Oesterreich S.Mol Cell Biol. 2010 Jan;30(2):399-412. Epub 2009 Nov 16.
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