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GATA3 Antibody (monoclonal) (M02)

Mouse monoclonal antibody raised against a partial recombinant GATA3.

     
  • WB - GATA3 Antibody (monoclonal) (M02) AT2162a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.52 KDa) .
    detail
  • WB - GATA3 Antibody (monoclonal) (M02) AT2162a
    GATA3 monoclonal antibody (M02), clone 2H5 Western Blot analysis of GATA3 expression in A-431 ( (Cat # AT2162a )
    detail
  • E - GATA3 Antibody (monoclonal) (M02) AT2162a
    Detection limit for recombinant GST tagged GATA3 is 0.03 ng/ml as a capture antibody.
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P23771
Other Accession NM_001002295
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 2H5
Calculated MW 47916 Da
Additional Information
Gene ID 2625
Other Names Trans-acting T-cell-specific transcription factor GATA-3, GATA-binding factor 3, GATA3
Target/Specificity GATA3 (NP_001002295.1, 103 a.a. ~ 200 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsGATA3 Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)
citation

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Background

This gene encodes a protein which belongs to the GATA family of transcription factors. The protein contains two GATA-type zinc fingers and is an important regulator of T-cell development and plays an important role in endothelial cell biology. Defects in this gene are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia.

References

Interleukin-9 polymorphism in infants with respiratory syncytial virus infection: an opposite effect in boys and girls. Schuurhof A, et al. Pediatr Pulmonol, 2010 Jun. PMID 20503287.GATA3 siRNA inhibits the binding of NFAT1 to interleukin-13 promoter in human T cells. Yao X, et al. Chin Med J (Engl), 2010 Mar 20. PMID 20368097.New genetic associations detected in a host response study to hepatitis B vaccine. Davila S, et al. Genes Immun, 2010 Apr. PMID 20237496.Lck mediates Th2 differentiation through effects on T-bet and GATA-3. Kemp KL, et al. J Immunol, 2010 Apr 15. PMID 20237292.GATA3 inhibits breast cancer metastasis through the reversal of epithelial-mesenchymal transition. Yan W, et al. J Biol Chem, 2010 Apr 30. PMID 20189993.

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$ 350.00
Cat# AT2162a
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