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GATA3 Antibody (monoclonal) (M02)
Mouse monoclonal antibody raised against a partial recombinant GATA3.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P23771 |
| Other Accession | NM_001002295 |
| Reactivity | Human |
| Host | mouse |
| Clonality | Monoclonal |
| Isotype | IgG2a Kappa |
| Clone Names | 2H5 |
| Calculated MW | 47916 Da |
| Gene ID | 2625 |
|---|---|
| Other Names | Trans-acting T-cell-specific transcription factor GATA-3, GATA-binding factor 3, GATA3 |
| Target/Specificity | GATA3 (NP_001002295.1, 103 a.a. ~ 200 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | GATA3 Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a protein which belongs to the GATA family of transcription factors. The protein contains two GATA-type zinc fingers and is an important regulator of T-cell development and plays an important role in endothelial cell biology. Defects in this gene are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia.
References
Interleukin-9 polymorphism in infants with respiratory syncytial virus infection: an opposite effect in boys and girls. Schuurhof A, et al. Pediatr Pulmonol, 2010 Jun. PMID 20503287.GATA3 siRNA inhibits the binding of NFAT1 to interleukin-13 promoter in human T cells. Yao X, et al. Chin Med J (Engl), 2010 Mar 20. PMID 20368097.New genetic associations detected in a host response study to hepatitis B vaccine. Davila S, et al. Genes Immun, 2010 Apr. PMID 20237496.Lck mediates Th2 differentiation through effects on T-bet and GATA-3. Kemp KL, et al. J Immunol, 2010 Apr 15. PMID 20237292.GATA3 inhibits breast cancer metastasis through the reversal of epithelial-mesenchymal transition. Yan W, et al. J Biol Chem, 2010 Apr 30. PMID 20189993.
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