FUT7 Antibody (monoclonal) (M03)
Mouse monoclonal antibody raised against a partial recombinant FUT7.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q11130 |
Other Accession | NM_004479 |
Reactivity | Human |
Host | mouse |
Clonality | Monoclonal |
Isotype | IgG2a Kappa |
Clone Names | 1C12 |
Calculated MW | 39239 Da |
Gene ID | 2529 |
---|---|
Other Names | Alpha-(1, 3)-fucosyltransferase 7, 241-, Fucosyltransferase 7, Fucosyltransferase VII, Fuc-TVII, FucT-VII, Galactoside 3-L-fucosyltransferase, Selectin ligand synthase, FUT7 |
Target/Specificity | FUT7 (NP_004470, 262 a.a. ~ 342 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
Dilution | WB~~1:500~1000 |
Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
Precautions | FUT7 Antibody (monoclonal) (M03) is for research use only and not for use in diagnostic or therapeutic procedures. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene is a Golgi stack membrane protein that is involved in the creation of sialyl-Lewis X antigens. The encoded protein can direct the synthesis of the E-selectin-binding sialyl-Lewis X moiety.
References
Association of genetic variants with hemorrhagic stroke in Japanese individuals. Yoshida T, et al. Int J Mol Med, 2010 Apr. PMID 20198315.Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals. Oguri M, et al. Am J Hypertens, 2010 Jan. PMID 19851296.alpha1,3 fucosyltransferase-VII up-regulates the mRNA of alpha5 integrin and its biological function. Wang QY, et al. J Cell Biochem, 2008 Aug 15. PMID 18452157.Overexpression of fucosyltransferase VII (FUT7) promotes embryo adhesion and implantation. Zhang Y, et al. Fertil Steril, 2009 Mar. PMID 18402946.Evaluation of urinary CA19-9 levels in bladder cancer patients classified according to the combinations of Lewis and Secretor blood group genotypes. Nagao K, et al. Int J Urol, 2007 Sep. PMID 17760744.
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