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FOXA1 Antibody (monoclonal) (M05)

Mouse monoclonal antibody raised against a partial recombinant FOXA1.

     
  • IF - FOXA1 Antibody (monoclonal) (M05) AT2084a
    Immunofluorescence of monoclonal antibody to FOXA1 on HeLa cell. [antibody concentration 10 ug/ml]
    detail
  • WB - FOXA1 Antibody (monoclonal) (M05) AT2084a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (37.4 KDa) .
    detail
  • WB - FOXA1 Antibody (monoclonal) (M05) AT2084a
    FOXA1 monoclonal antibody (M05), clone 3C1. Western Blot analysis of FOXA1 expression in HepG2 ( (Cat # AT2084a )
    detail
  • WB - FOXA1 Antibody (monoclonal) (M05) AT2084a
    FOXA1 monoclonal antibody (M05), clone 3C1 Western Blot analysis of FOXA1 expression in MCF-7 ( (Cat # AT2084a )
    detail
  • IHC - FOXA1 Antibody (monoclonal) (M05) AT2084a
    Immunoperoxidase of monoclonal antibody to FOXA1 on formalin-fixed paraffin-embedded human prostate. [antibody concentration 1.5 ug/ml]
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IHC, IF
Primary Accession P55317
Other Accession NM_004496
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG1 Kappa
Clone Names 3C1
Calculated MW 49148 Da
Additional Information
Gene ID 3169
Other Names Hepatocyte nuclear factor 3-alpha, HNF-3-alpha, HNF-3A, Forkhead box protein A1, Transcription factor 3A, TCF-3A, FOXA1, HNF3A, TCF3A
Target/Specificity FOXA1 (NP_004487, 367 a.a. ~ 472 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsFOXA1 Antibody (monoclonal) (M05) is for research use only and not for use in diagnostic or therapeutic procedures.
Citations (0)
citation

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Background

This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver.

References

[Diagnostic and prognostic significance of FOXA1 expression in molecular subtypes of breast invasive ductal carcinomas] Liu N, et al. Zhonghua Yi Xue Za Zhi, 2010 May 25. PMID 20646630.FOXA1 is an essential determinant of ERalpha expression and mammary ductal morphogenesis. Bernardo GM, et al. Development, 2010 Jun. PMID 20501593.Loss of FOXA1/2 is essential for the epithelial-to-mesenchymal transition in pancreatic cancer. Song Y, et al. Cancer Res, 2010 Mar 1. PMID 20160041.ErbB3 binding protein 1 represses metastasis-promoting gene anterior gradient protein 2 in prostate cancer. Zhang Y, et al. Cancer Res, 2010 Jan 1. PMID 20048076.Forkhead box A1 transcriptional pathway in KRT7-expressing esophageal squamous cell carcinomas with extensive lymph node metastasis. Sano M, et al. Int J Oncol, 2010 Feb. PMID 20043065.

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$ 350.00
Cat# AT2084a
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Availability: 7-10 days
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