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FKBP1A Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a full length recombinant FKBP1A.

     
  • WB - FKBP1A Antibody (monoclonal) (M01) AT2055a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (37.62 KDa) .
    detail
  • WB - FKBP1A Antibody (monoclonal) (M01) AT2055a
    FKBP1A monoclonal antibody (M01), clone 1E5-A12 Western Blot analysis of FKBP1A expression in HL-60 ( (Cat # AT2055a )
    detail
  • WB - FKBP1A Antibody (monoclonal) (M01) AT2055a
    Western Blot analysis of FKBP1A expression in transfected 293T cell line by FKBP1A monoclonal antibody (M01), clone 1E5-A12.

    Lane 1: FKBP1A transfected lysate(12 KDa).
    Lane 2: Non-transfected lysate.
    detail
  • E - FKBP1A Antibody (monoclonal) (M01) AT2055a
    Detection limit for recombinant GST tagged FKBP1A is 3 ng/ml as a capture antibody.
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P62942
Other Accession BC005147
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG1 kappa
Clone Names 1E5-A12
Calculated MW 11951 Da
Additional Information
Gene ID 2280
Other Names Peptidyl-prolyl cis-trans isomerase FKBP1A, PPIase FKBP1A, 12 kDa FK506-binding protein, 12 kDa FKBP, FKBP-12, Calstabin-1, FK506-binding protein 1A, FKBP-1A, Immunophilin FKBP12, Rotamase, FKBP1A, FKBP1, FKBP12
Target/Specificity FKBP1A (AAH05147, 1 a.a. ~ 108 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsFKBP1A Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)
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Background

The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium. Multiple alternatively spliced variants, encoding the same protein, have been identified. The human genome contains five pseudogenes related to this gene, at least one of which is transcribed.

References

1.Protein-protein interactions: an application of tus-ter mediated protein microarray system.Sitaraman K, Chatterjee DK.Methods Mol Biol. 2011;723:185-200.

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$ 350.00
Cat# AT2055a
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Availability: 7-10 days
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