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>   home   >   Products   >   Primary Antibodies   >   ETV6 Antibody (monoclonal) (M01)   

ETV6 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a full length recombinant ETV6.

     
  • WB - ETV6 Antibody (monoclonal) (M01) AT1956a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (75.46 KDa) .
    detail
  • WB - ETV6 Antibody (monoclonal) (M01) AT1956a
    ETV6 monoclonal antibody (M01), clone 3B10 Western Blot analysis of ETV6 expression in Jurkat ( (Cat # AT1956a )
    detail
  • IHC - ETV6 Antibody (monoclonal) (M01) AT1956a
    Immunoperoxidase of monoclonal antibody to ETV6 on formalin-fixed paraffin-embedded human placenta. [antibody concentration 3 ug/ml]
    detail
  • E - ETV6 Antibody (monoclonal) (M01) AT1956a
    Detection limit for recombinant GST tagged ETV6 is approximately 0.1ng/ml as a capture antibody.
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IHC, E
Primary Accession P41212
Other Accession BC043399
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG1 Kappa
Clone Names 3B10
Calculated MW 53000 Da
Additional Information
Gene ID 2120
Other Names Transcription factor ETV6, ETS translocation variant 6, ETS-related protein Tel1, Tel, ETV6, TEL, TEL1
Target/Specificity ETV6 (AAH43399, 1 a.a. ~ 452 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsETV6 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Citations (0)
citation

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Background

This gene encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N-terminal pointed (PNT) domain that is involved in protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma.

References

1.ETV6 mutations in early immature human T cell leukemias.Van Vlierberghe P, Ambesi-Impiombato A, Perez-Garcia A, Haydu JE, Rigo I, Hadler M, Tosello V, Della Gatta G, Paietta E, Racevskis J, Wiernik PH, Luger SM, Rowe JM, Rue M, Ferrando AA.J Exp Med. 2011 Dec 19;208(13):2571-9. Epub 2011 Dec 12.2.The ETS Family Member TEL Binds to Nuclear Receptors RAR and RXR and Represses Gene Activation.Meester-Smoor MA, Janssen MJ, Ter Haar WM, van Wely KH, Aarnoudse AJ, van Oord G, van Tilburg GB, Zwarthoff EC.PLoS One. 2011;6(9):e23620. Epub 2011 Sep 16.

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$ 350.00
Cat# AT1956a
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Availability: 7-10 days
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