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DENR Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant DENR.

     
  • WB - DENR Antibody (monoclonal) (M01) AT1754a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (34.65 KDa) .
    detail
  • WB - DENR Antibody (monoclonal) (M01) AT1754a
    Western Blot analysis of DENR expression in transfected 293T cell line by DENR monoclonal antibody (M01), clone 1H3.

    Lane 1: DENR transfected lysate(22.092 KDa).
    Lane 2: Non-transfected lysate.
    detail
  • WB - DENR Antibody (monoclonal) (M01) AT1754a
    Western blot analysis of DENR over-expressed 293 cell line, cotransfected with DENR Validated Chimera RNAi ( (Cat # AT1754a )
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession O43583
Other Accession NM_003677
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 1H3
Calculated MW 22092 Da
Additional Information
Gene ID 8562
Other Names Density-regulated protein, DRP, Protein DRP1, Smooth muscle cell-associated protein 3, SMAP-3, DENR, DRP1
Target/Specificity DENR (NP_003668, 1 a.a. ~ 81 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsDENR Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Citations (0)
citation

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Background

This gene encodes a protein whose expression was found to increase in cultured cells at high density but not during growth arrest. This gene was also shown to have increased expression in cells overexpressing HER-2/neu proto-oncogene. The protein contains an SUI1 domain. In budding yeast, SUI1 is a translation initiation factor that along with eIF-2 and the initiator tRNA-Met, directs the ribosome to the proper translation start site. Proteins similar to SUI have been found in mammals, insects, and plants.

References

Post-transcriptional control of the MCT-1-associated protein DENR/DRP by RNA-binding protein AUF1. Mazan-Mamczarz K, et al. Cancer Genomics Proteomics, 2007 May-Jun. PMID 17878526.A novel mitochondrial ubiquitin ligase plays a critical role in mitochondrial dynamics. Yonashiro R, et al. EMBO J, 2006 Aug 9. PMID 16874301.A human protein-protein interaction network: a resource for annotating the proteome. Stelzl U, et al. Cell, 2005 Sep 23. PMID 16169070.The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932.

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$ 350.00
Cat# AT1754a
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Availability: 7-10 days
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