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DDX6 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a full length recombinant DDX6.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC |
|---|---|
| Primary Accession | P26196 |
| Other Accession | BC065007 |
| Reactivity | Human |
| Host | mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 kappa |
| Clone Names | 3D2 |
| Calculated MW | 54417 Da |
| Gene ID | 1656 |
|---|---|
| Other Names | Probable ATP-dependent RNA helicase DDX6, ATP-dependent RNA helicase p54, DEAD box protein 6, Oncogene RCK, DDX6, HLR2, RCK |
| Target/Specificity | DDX6 (AAH65007, 1 a.a. ~ 483 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | DDX6 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the DEAD box protein family. The protein is an RNA helicase found in P-bodies and stress granules, and functions in translation suppression and mRNA degradation. It is required for microRNA-induced gene silencing.
References
1.DDX6 localizes to nuage structures and the annulus of mammalian spermatogenic cells.Kawahara C, Yokota S, Fujita HHistochem Cell Biol. 2013 Oct 20.2.The DEAD-box RNA Helicase DDX6 is Required for Efficient Encapsidation of a Retroviral Genome.Yu SF, Lujan P, Jackson DL, Emerman M, Linial ML.PLoS Pathog. 2011 Oct;7(10):e1002303. Epub 2011 Oct 13.3.Rck/p54 interacts with APP mRNA as part of a multi-protein complex and enhances APP mRNA and protein expression in neuronal cell lines.Broytman O, Westmark PR, Gurel Z, Malter JS.Neurobiol Aging. 2008 Mar 28 [Epub ahead of print]
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