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CRTAP Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant CRTAP.

     
  • WB - CRTAP Antibody (monoclonal) (M01) AT1637a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.19 KDa) .
    detail
  • WB - CRTAP Antibody (monoclonal) (M01) AT1637a
    CRTAP monoclonal antibody (M01), clone 4D9 Western Blot analysis of CRTAP expression in HeLa ( (Cat # AT1637a )
    detail
  • IHC - CRTAP Antibody (monoclonal) (M01) AT1637a
    Immunoperoxidase of monoclonal antibody to CRTAP on formalin-fixed paraffin-embedded human kidney. [antibody concentration 3 ug/ml]
    detail
  • E - CRTAP Antibody (monoclonal) (M01) AT1637a
    Detection limit for recombinant GST tagged CRTAP is approximately 0.03ng/ml as a capture antibody.
    detail
  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IHC, E
Primary Accession O75718
Other Accession NM_006371
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 4D9
Calculated MW 46562 Da
Additional Information
Gene ID 10491
Other Names Cartilage-associated protein, CRTAP, CASP
Target/Specificity CRTAP (NP_006362, 307 a.a. ~ 401 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsCRTAP Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)
citation

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Background

The protein encoded by this gene is similar to the chicken and mouse CRTAP genes. The encoded protein is a scaffolding protein that may influence the activity of at least one member of the cytohesin/ARNO family in response to specific cellular stimuli. Defects in this gene are associated with osteogenesis imperfecta, a connective tissue disorder characterized by bone fragility and low bone mass.

References

1.Severe osteogenesis imperfecta in cyclophilin B-deficient mice.Choi JW, Sutor SL, Lindquist L, Evans GL, Madden BJ, Bergen HR 3rd, Hefferan TE, Yaszemski MJ, Bram RJ.PLoS Genet. 2009 Dec;5(12):e1000750. Epub 2009 Dec 4.2.Prolyl 3-hydroxylase 1 and CRTAP are mutually stabilizing in the endoplasmic reticulum collagen prolyl 3-hydroxylation complex.Chang W, Barnes AM, Cabral WA, Bodurtha JN, Marini JC.Hum Mol Genet. 2010 Jan 15;19(2):223-34. Epub 2009 Oct 21.

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$ 350.00
Cat# AT1637a
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