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CKB Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a full length recombinant CKB.

     
  • IF - CKB Antibody (monoclonal) (M01) AT1543a
    Immunofluorescence of monoclonal antibody to CKB on HeLa cell. [antibody concentration 30 ug/ml]
    detail
  • WB - CKB Antibody (monoclonal) (M01) AT1543a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (67.65 KDa) .
    detail
  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IF
Primary Accession P12277
Other Accession BC001190
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG1 Kappa
Clone Names 3D5-3D11
Calculated MW 42644 Da
Additional Information
Gene ID 1152
Other Names Creatine kinase B-type, B-CK, Creatine kinase B chain, CKB, CKBB
Target/Specificity CKB (AAH01190, 1 a.a. ~ 381 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsCKB Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)
citation

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Background

The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in brain as well as in other tissues, and as a heterodimer with a similar muscle isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family. A pseudogene of this gene has been characterized.

References

Reduced creatine kinase B activity in multiple sclerosis normal appearing white matter. Steen C, et al. PLoS One, 2010 May 25. PMID 20520825.Reduced creatine kinase as a central and peripheral biomarker in Huntington's disease. Kim J, et al. Biochim Biophys Acta, 2010 Jul-Aug. PMID 20460152.Defining the human deubiquitinating enzyme interaction landscape. Sowa ME, et al. Cell, 2009 Jul 23. PMID 19615732.Proteome analysis of schizophrenia patients Wernicke's area reveals an energy metabolism dysregulation. Martins-de-Souza D, et al. BMC Psychiatry, 2009 Apr 30. PMID 19405953.Prefrontal cortex shotgun proteome analysis reveals altered calcium homeostasis and immune system imbalance in schizophrenia. Martins-de-Souza D, et al. Eur Arch Psychiatry Clin Neurosci, 2009 Apr. PMID 19165527.

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$ 350.00
Cat# AT1543a
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