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CDK5RAP3 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a full length recombinant CDK5RAP3.

     
  • IF - CDK5RAP3 Antibody (monoclonal) (M01) AT1477a
    Immunofluorescence of monoclonal antibody to CDK5RAP3 on HeLa cell. [antibody concentration 10 ug/ml]
    detail
  • WB - CDK5RAP3 Antibody (monoclonal) (M01) AT1477a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (81.51 KDa) .
    detail
  • WB - CDK5RAP3 Antibody (monoclonal) (M01) AT1477a
    CDK5RAP3 monoclonal antibody (M01), clone 1G4 Western Blot analysis of CDK5RAP3 expression in A-431 ( (Cat # AT1477a )
    detail
  • IHC - CDK5RAP3 Antibody (monoclonal) (M01) AT1477a
    Immunoperoxidase of monoclonal antibody to CDK5RAP3 on formalin-fixed paraffin-embedded human colon. [antibody concentration 3 ug/ml]
    detail
  • E - CDK5RAP3 Antibody (monoclonal) (M01) AT1477a
    Detection limit for recombinant GST tagged CDK5RAP3 is approximately 0.03ng/ml as a capture antibody.
    detail
  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IHC, IF, E
Primary Accession Q96JB5
Other Accession BC009957
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG1 Kappa
Clone Names 1G4
Calculated MW 56921 Da
Additional Information
Gene ID 80279
Other Names CDK5 regulatory subunit-associated protein 3, CDK5 activator-binding protein C53, Protein HSF-27, CDK5RAP3, IC53
Target/Specificity CDK5RAP3 (AAH09957, 1 a.a. ~ 506 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsCDK5RAP3 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)
citation

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Background

Neuronal CDC2-like kinase, which is involved in the regulation of neuronal differentiation, is composed of a catalytic subunit, CDK5, and an activating subunit, p25NCK5A. The protein encoded by this gene binds to p25NCK5A and therefore may be involved in neuronal differentiation. The encoded protein, which may be a substrate of neuronal CDC2-like kinase, has also been found in vascular endothelial cells, where it mediates cell proliferation.

References

1.Suppression of the novel ER protein Maxer by mutant ataxin-1 in Bergman glia contributes to non-cell-autonomous toxicity.Shiwaku H, Yoshimura N, Tamura T, Sone M, Ogishima S, Watase K, Tagawa K, Okazawa H.EMBO J. 2010 Jun 8. [Epub ahead of print]

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$ 350.00
Cat# AT1477a
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