CCR2 Antibody (monoclonal) (M01A)
Mouse monoclonal antibody raised against a partial recombinant CCR2.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
---|---|
Primary Accession | P41597 |
Other Accession | NM_000648 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Isotype | IgM Kappa |
Clone Names | 4D12 |
Calculated MW | 41915 Da |
Gene ID | 729230 |
---|---|
Other Names | C-C chemokine receptor type 2, C-C CKR-2, CC-CKR-2, CCR-2, CCR2, Monocyte chemoattractant protein 1 receptor, MCP-1-R, CD192, CCR2, CMKBR2 |
Target/Specificity | CCR2 (NP_000639, 1 a.a. ~ 42 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
Dilution | WB~~1:500~1000 |
Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
Precautions | CCR2 Antibody (monoclonal) (M01A) is for research use only and not for use in diagnostic or therapeutic procedures. |
- Primary Antibodies
- Cancer
- Cardiovascular
- Immunology
- Microbiology
- Signal Transduction
- Antibody Collections
- GPCR Antibodies
- Druggable G protein-coupled receptors (GPCRs)
- Viral process
- Host-virus interaction
- Immune system process
- Chemokine receptor family
- Chemokine signaling
- Inflammation mediated by chemokine and cytokine signaling
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This gene is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the gene. [provided by RefSeq]
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