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>   home   >   Products   >   Primary Antibodies   >   Antibody Collections   >   Anti-Wnt-Pathway (plus Lgr5) Antibodies   >   CAMK2B Antibody (monoclonal) (M06)   

CAMK2B Antibody (monoclonal) (M06)

Mouse monoclonal antibody raised against a partial recombinant CAMK2B.

     
  • IF - CAMK2B Antibody (monoclonal) (M06) AT1377a
    Immunofluorescence of monoclonal antibody to CAMK2B on HeLa cell. [antibody concentration 25 ug/ml]
    detail
  • WB - CAMK2B Antibody (monoclonal) (M06) AT1377a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.52 KDa) .
    detail
  • WB - CAMK2B Antibody (monoclonal) (M06) AT1377a
    CAMK2B monoclonal antibody (M06), clone 6D6. Western Blot analysis of CAMK2B expression in HeLa((Cat # AT1377a )
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IF
Primary Accession Q13554
Other Accession NM_172081
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG1 Kappa
Clone Names 6D6
Calculated MW 72678 Da
Additional Information
Gene ID 816
Other Names Calcium/calmodulin-dependent protein kinase type II subunit beta, CaM kinase II subunit beta, CaMK-II subunit beta, CAMK2B, CAM2, CAMK2, CAMKB
Target/Specificity CAMK2B (NP_742078, 405 a.a. ~ 502 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsCAMK2B Antibody (monoclonal) (M06) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)
citation

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Background

The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a beta chain. It is possible that distinct isoforms of this chain have different cellular localizations and interact differently with calmodulin. Eight transcript variants encoding eight distinct isoforms have been identified for this gene.

References

Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis. Need AC, et al. Eur J Hum Genet, 2009 Jul. PMID 19156168.A common variant in DRD3 receptor is associated with autism spectrum disorder. de Krom M, et al. Biol Psychiatry, 2009 Apr 1. PMID 19058789.Motor protein-dependent transport of AMPA receptors into spines during long-term potentiation. Correia SS, et al. Nat Neurosci, 2008 Apr. PMID 18311135.Genetically encoded probe for fluorescence lifetime imaging of CaMKII activity. Kwok S, et al. Biochem Biophys Res Commun, 2008 May 2. PMID 18302935.

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$ 350.00
Cat# AT1377a
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