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BAG5 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a full length recombinant BAG5.

     
  • WB - BAG5 Antibody (monoclonal) (M01) AT1263a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (74.91 KDa) .
    detail
  • WB - BAG5 Antibody (monoclonal) (M01) AT1263a
    BAG5 monoclonal antibody (M01), clone 2E2. Western Blot analysis of BAG5 expression in HeLa.
    detail
  • WB - BAG5 Antibody (monoclonal) (M01) AT1263a
    Western Blot analysis of BAG5 expression in transfected 293T cell line by BAG5 monoclonal antibody (M01), clone 2E2.

    Lane 1: BAG5 transfected lysate (Predicted MW: 51.2 KDa).
    Lane 2: Non-transfected lysate.
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q9UL15
Other Accession BC050551
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG1 kappa
Clone Names 2E3
Calculated MW 51200 Da
Additional Information
Gene ID 9529
Other Names BAG family molecular chaperone regulator 5, BAG-5, Bcl-2-associated athanogene 5, BAG5, KIAA0873
Target/Specificity BAG5 (AAH50551, 1 a.a. ~ 447 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsBAG5 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)
citation

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Background

The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. Three transcript variants encoding two different isoforms have been found for this gene.

References

Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. Talmud PJ, et al. Am J Hum Genet, 2009 Nov. PMID 19913121.Defining the human deubiquitinating enzyme interaction landscape. Sowa ME, et al. Cell, 2009 Jul 23. PMID 19615732.Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. Kimura K, et al. Genome Res, 2006 Jan. PMID 16344560.BAG5 inhibits parkin and enhances dopaminergic neuron degeneration. Kalia SK, et al. Neuron, 2004 Dec 16. PMID 15603737.

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$ 350.00
Cat# AT1263a
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Availability: 7-10 days
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