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AVPR1A Antibody (monoclonal) (M07)

Mouse monoclonal antibody raised against a partial recombinant AVPR1A.

     
  • WB - AVPR1A Antibody (monoclonal) (M07) AT1248a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (31.46 KDa) .
    detail
  • WB - AVPR1A Antibody (monoclonal) (M07) AT1248a
    Western Blot analysis of AVPR1A expression in transfected 293T cell line by AVPR1A monoclonal antibody (M07), clone 7B8.

    Lane 1: AVPR1A transfected lysate(46.8 KDa).
    Lane 2: Non-transfected lysate.
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession P37288
Other Accession NM_000706
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 7B8
Calculated MW 46800 Da
Additional Information
Gene ID 552
Other Names Vasopressin V1a receptor, V1aR, AVPR V1a, Antidiuretic hormone receptor 1a, Vascular/hepatic-type arginine vasopressin receptor, AVPR1A, AVPR1
Target/Specificity AVPR1A (NP_000697, 1 a.a. ~ 52 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsAVPR1A Antibody (monoclonal) (M07) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)
citation

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Background

The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1B, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor mediates cell contraction and proliferation, platelet aggregation, release of coagulation factor and glycogenolysis.

References

Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.Association study between single nucleotide polymorphisms in promoter region of AVPR1A and Korean autism spectrum disorders. Yang SY, et al. Neurosci Lett, 2010 Aug 2. PMID 20546835.Association study of 182 candidate genes in anorexia nervosa. Pinheiro AP, et al. Am J Med Genet B Neuropsychiatr Genet, 2010 Jul. PMID 20468064.Family-based association study of microsatellites in the 5' flanking region of AVPR1A with autism spectrum disorder in the Korean population. Yang SY, et al. Psychiatry Res, 2010 Jun 30. PMID 20452058.Association of polymorphisms in genes regulating the corticotropin-releasing factor system with antidepressant treatment response. Binder EB, et al. Arch Gen Psychiatry, 2010 Apr. PMID 20368512.

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$ 350.00
Cat# AT1248a
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Availability: 7-10 days
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