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ADH4 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant ADH4.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P08319 |
| Other Accession | NM_000670 |
| Reactivity | Human |
| Host | mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 Kappa |
| Clone Names | 3C5 |
| Calculated MW | 40222 Da |
| Gene ID | 127 |
|---|---|
| Other Names | Alcohol dehydrogenase 4, Alcohol dehydrogenase class II pi chain, ADH4 |
| Target/Specificity | ADH4 (NP_000661, 52 a.a. ~ 150 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | ADH4 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes class II alcohol dehydrogenase 4 pi subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class II alcohol dehydrogenase is a homodimer composed of 2 pi subunits. It exhibits a high activity for oxidation of long-chain aliphatic alcohols and aromatic alcohols and is less sensitive to pyrazole. This gene is localized to chromosome 4 in the cluster of alcohol dehydrogenase genes.
References
Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia. Jugessur A, et al. PLoS One, 2010 Jul 9. PMID 20634891.Association of ADH4 genetic variants with alcohol dependence risk and related phenotypes: results from a larger multicenter association study. Preuss UW, et al. Addict Biol, 2010 Jul 9. PMID 20626721.A Large-scale genetic association study of esophageal adenocarcinoma risk. Liu CY, et al. Carcinogenesis, 2010 Jul. PMID 20453000.Identification of a FOXA-dependent enhancer of human alcohol dehydrogenase 4 (ADH4). Pochareddy S, et al. Gene, 2010 Jul 15. PMID 20363298.Cluster headache is associated with the alcohol dehydrogenase 4 (ADH4) gene. Rainero I, et al. Headache, 2010 Jan. PMID 19925625.
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