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ACYP2 Antibody (monoclonal) (M06)
Mouse monoclonal antibody raised against a partial recombinant ACYP2.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P14621 |
| Other Accession | NM_138448 |
| Reactivity | Human |
| Host | mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 Kappa |
| Clone Names | 2H7 |
| Calculated MW | 11140 Da |
| Gene ID | 98 |
|---|---|
| Other Names | Acylphosphatase-2, Acylphosphatase, muscle type isozyme, Acylphosphate phosphohydrolase 2, ACYP2, ACYP |
| Target/Specificity | ACYP2 (NP_612457, 1 a.a. ~ 98 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | ACYP2 Antibody (monoclonal) (M06) is for research use only and not for use in diagnostic or therapeutic procedures. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Acylphosphatase can hydrolyze the phosphoenzyme intermediate of different membrane pumps, particularly the Ca2+/Mg2+-ATPase from sarcoplasmic reticulum of skeletal muscle. Two isoenzymes have been isolated, called muscle acylphosphatase and erythrocyte acylphosphatase on the basis of their tissue localization. This gene encodes the muscle-type isoform (MT). An increase of the MT isoform is associated with muscle differentiation.
References
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.Association of genetic variants with hemorrhagic stroke in Japanese individuals. Yoshida T, et al. Int J Mol Med, 2010 Apr. PMID 20198315.Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals. Oguri M, et al. Am J Hypertens, 2010 Jan. PMID 19851296.Mutational analysis of the aggregation-prone and disaggregation-prone regions of acylphosphatase. Calamai M, et al. J Mol Biol, 2009 Apr 10. PMID 18809411.Replication of a genome-wide case-control study of esophageal squamous cell carcinoma. Ng D, et al. Int J Cancer, 2008 Oct 1. PMID 18649358.
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