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> home > Products > Primary Antibodies > Cancer > Anti-Protein Kinase C delta-Binding Protein (RABBIT) Antibody
Anti-Protein Kinase C delta-Binding Protein (RABBIT) Antibody
Protein Kinase C delta-Binding Protein Antibody
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- BACKGROUND
| Host | Rabbit |
|---|---|
| Conjugate | Unconjugated |
| Target Species | Human |
| Reactivity | Human |
| Clonality | Polyclonal |
Application 
| WB, IHC, E, I, LCI |
| Application Note | Anti-Protein Kinase C delta Binding Protein antibody is tested in immunohistochemistry and ELISA and useful for Western Blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~37kDa corresponding to the appropriate cell lysate or extract. |
| Physical State | Liquid (sterile filtered) |
| Buffer | 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 |
| Immunogen | Protein Kinase C delta-Binding Protein affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to the C-terminal region of human Protein Kinase C delta-Binding Protein. |
| Stabilizer | 30% Glycerol |
| Gene ID | 112464 |
|---|---|
| Other Names | 112464 |
| Purity | Anti-Protein Kinase C delta-Binding Protein was affinity purified from monospecific antiserum by immunoaffinity chromatography. A BLAST analysis was used to suggest cross-reactivity with rat, human, and mouse based on 100% sequence homology. Cross-reactivity with Protein Kinase C delta-Binding Protein from other sources has not been determined. |
| Storage Condition | Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. |
| Precautions Note | This product is for research use only and is not intended for therapeutic or diagnostic applications. |
| Name | CAVIN3 (HGNC:9400) |
|---|---|
| Synonyms | PRKCDBP, SRBC |
| Function | Regulates the traffic and/or budding of caveolae (PubMed:19262564). Plays a role in caveola formation in a tissue- specific manner. Required for the formation of caveolae in smooth muscle but not in the lung and heart endothelial cells. Regulates the equilibrium between cell surface-associated and cell surface- dissociated caveolae by promoting the rapid release of caveolae from the cell surface. Plays a role in the regulation of the circadian clock. Modulates the period length and phase of circadian gene expression and also regulates expression and interaction of the core clock components PER1/2 and CRY1/2 (By similarity). |
| Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:Q91VJ2}. Membrane, caveola. Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q91VJ2}. Note=Localizes in the caveolae in a caveolin-dependent manner. |
| Tissue Location | Skeletal muscle, liver, stomach, lung, kidney and heart (at protein level). Strongly expressed in mammary and epithelial cells. |
Research Areas
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
Background
Protein Kinase C delta-Binding Protein antibody, once activated by diacylglycerol, phosphorylates various cellular proteins. It also functions as a receptor for phorbol esters and may be a factor in antigen-dependent control of B-cell function. Anti-Protein Kinase C delta-Binding Protein antibody is ideal for researchers interested in Neuroscience, Cancer, and Signal Transduction research.
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$ 475.00
Cat# ASR5682
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