Ubiquitin Antibody
Ubiquitin Antibody, Clone FK1
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P0CG47 |
---|---|
Other Accession | BAC56955.1 |
Host | Mouse |
Clonality | Monoclonal |
Target/Specificity | Ubiquitin |
Other Names | Polyubiquitin B Antibody, RPS27A Antibody, UBA52 Antibody, UBB Antibody, UBC Antibody, ubiquitin B Antibody |
Clone Names | Ubiquitin |
Immunogen | Human Ubiquitin conjugated lysozyme |
Purification | Gel filtration |
Storage | -20ºC |
Storage Buffer | 10mM phosphate buffer, 0.15M NaCl pH7.4, 0.1% sodium azide *Storage buffer may change when conjugated |
Shipping Temperature | Blue Ice or 4ºC |
Certificate of Analysis | A 1:5000 dilution of SMC-213 was sufficient for detection of ubiquitin conjugates in 2.5 µg of HeLa cell lysate by electrochemiluminescence analysis using goat anti-mouse IgG:HRP as the secondary antibody. |
Cellular Localization | Cytoplasm | Nucleus |
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Provided below are standard protocols that you may find useful for product applications.
Background
Ubiquitin is a small protein found ubiquitously in all tissue types and acts as a post translational modification. It can bind to its substrate either as a single ubiquitin molecule or in a chain. It is involved in many regulatory processes, which include proteasomal degradation, signal transduction, DNA repair, endocytosis and autophagy.
References
1. Chen J., & Chen Z. (2013). Curr Opin Immunol. (1): 4-12.
2. Shaid S., Brandts C., Serve H., & Dikic I. (2013). Cell Death Differ. 20(1): 21-30.
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