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DDDDK Antibody [1D1B12] (biotin)
![WB - DDDDK Antibody [1D1B12] (biotin) ASC12045](/assets/uploads/products/201704/ASC12045_WB_1.jpg)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P60709 |
| Other Accession | 60 |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG |
| Calculated MW | 41737 Da |
| Application Notes | Biotin-DDDDK antibody can be used for detection of DDDDK by Western blot at 0.5 - 1 µ/ml. |
| Gene ID | 60 |
|---|---|
| Other Names | Biotin-DDDDK, DDDDK, FLAG, FLAGtag, flag-tag |
| Precautions | DDDDK Antibody [1D1B12] (biotin) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ACTB |
|---|---|
| Function | Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells (PubMed:25255767, PubMed:29581253). Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction (PubMed:29581253). In addition to their role in the cytoplasmic cytoskeleton, G- and F- actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA (PubMed:29925947). Part of the ACTR1A/ACTB filament around which the dynactin complex is built. The dynactin multiprotein complex activates the molecular motor dynein for ultra-processive transport along microtubules (By similarity). |
| Cellular Location | Cytoplasm, cytoskeleton. Nucleus Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Epitope tags provide a method to localize gene products in a variety of cell types, study the topology of proteins and protein complexes, identify associated proteins, and characterize newly identified, low abundance or poorly immunogenic proteins when protein specific antibodies are not available. DDDDK-tag is one of the more popular epitope tags for expressed recombinant proteins.
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