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AGTR1 Antibody

     
  • WB - AGTR1 Antibody ASC10977
    Western blot analysis of AGTR1 in mouse kidney tissue lysate with AGTR1 antibody at (A) 1 and (B) 2 µg/mL.
    detail
  • IHC - AGTR1 Antibody ASC10977
    Immunohistochemistry of AGTR1 in mouse kidney tissue with AGTR1 antibody at 2.5 µg/mL.
    detail
  • IF - AGTR1 Antibody ASC10977
    Immunofluorescence of AGTR1 in Mouse Kidney cells with AGTR1 antibody at 20 µg/mL.
    detail
Western blot analysis of AGTR1 in mouse kidney tissue lysate with AGTR1 antibody at (A) 1 and (B) 2 µg/mL.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, E
Primary Accession P30556
Other Accession EAW78909, 119599315
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 41061 Da
Application Notes AGTR1 antibody can be used for detection of AGTR1 by Western blot at 1 - 2 µg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 µg/mL. For immunofluorescence start at 20 µg/mL.
Additional Information
Gene ID 185
Target/Specificity AGTR1;
Reconstitution & Storage AGTR1 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
PrecautionsAGTR1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name AGTR1 (HGNC:336)
Function Receptor for angiotensin II, a vasoconstricting peptide, which acts as a key regulator of blood pressure and sodium retention by the kidney (PubMed:15611106, PubMed:1567413, PubMed:25913193, PubMed:26420482, PubMed:30639100, PubMed:32079768, PubMed:8987975). The activated receptor in turn couples to G-alpha proteins G(q) (GNAQ, GNA11, GNA14 or GNA15) and thus activates phospholipase C and increases the cytosolic Ca(2+) concentrations, which in turn triggers cellular responses such as stimulation of protein kinase C (PubMed:15611106).
Cellular Location Cell membrane; Multi-pass membrane protein
Tissue Location Liver, lung, adrenal and adrenocortical adenomas.
Research Areas
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$ 379.00
Cat# ASC10977
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