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LIAR Antibody

     
  • WB - LIAR Antibody ASC10942
    Western blot analysis of LIAR in mouse kidney tissue lysate with LIAR antibody at 1 µg/mL in (A) the absence and (B) the presence of blocking peptide.
    detail
  • IHC - LIAR Antibody ASC10942
    Immunohistochemistry of LIAR in mouse kidney tissue with LIAR antibody at 2.5 µg/mL.
    detail
  • IF - LIAR Antibody ASC10942
    Immunofluorescence of LIAR in Mouse Kidney cells with LIAR antibody at 20 µg/mL.
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, E
Primary Accession Q6NXT1
Other Accession NP_620152, 20270347
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 32505 Da
Application Notes LIAR antibody can be used for detection of LIAR by Western blot at 1 µg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 µg/mL. For immunofluorescence start at 20 µg/mL.
Additional Information
Gene ID 129138
Target/Specificity ANKRD54;
Reconstitution & Storage LIAR antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
PrecautionsLIAR Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ANKRD54
Synonyms LIAR
Function Plays an important role in regulating intracellular signaling events associated with erythroid terminal differentiation.
Cellular Location Nucleus. Cytoplasm. Midbody. Note=Shuttles between nucleus and cytoplasm during the cell cycle. EPO stimulation induces nuclear accumulation (By similarity).
Research Areas
Citations (0)
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Background

LIAR Antibody: Ankyrin (ANK) repeats mediate protein-protein interactions in diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20. ANK repeats may occur in combinations with other types of domains. The structural repeat unit contains two anti-parallel helices and a beta-hairpin, with repeats stacked in a superhelical arrangement. LIAR, also known as ANKRD54, is a recently identified ANK repeat-containing protein that is predominantly expressed in tissues rich in cilliated cells, such as olfactory sensory neurons and is predicted to be important to cilia. At least three isoforms of LIAR are known to exist.

References

Li J, Mahajan A, and Tsai MD. Ankyrin repeat: a unique motif mediating protein-protein interactions. Biochemistry2006; 45:15168-78.


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$ 379.00
Cat# ASC10942
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