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> home > Products > Primary Antibodies > Antibody Collections > Recombinant Antibodies > Anti-PLAUR / uPAR / CD87 Reference Antibody (ATN-658)
Anti-PLAUR / uPAR / CD87 Reference Antibody (ATN-658)
Recombinant Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| FC, E, FTA |
|---|---|
| Primary Accession | Q03405 |
| Reactivity | Human, Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Calculated MW | 145 KDa |
| Target/Specificity | PLAUR / uPAR / CD87 |
|---|---|
| Endotoxin | < 0.001EU/ µg,determined by LAL method. |
| Conjugation | Unconjugated |
| Expression system | CHO Cell |
| Format | Purified monoclonal antibody supplied in PBS, pH6.0, without preservative.This antibody is purified through a protein A column. |
| Name | PLAUR |
|---|---|
| Synonyms | MO3, UPAR |
| Function | Acts as a receptor for urokinase plasminogen activator (PubMed:15677461). Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form. |
| Cellular Location | Cell membrane. Cell projection, invadopodium membrane Note=Colocalized with FAP (seprase) preferentially at the cell surface of invadopodia membrane in a cytoskeleton-, integrin- and vitronectin- dependent manner. [Isoform 2]: Secreted {ECO:0000250|UniProtKB:P49616} |
| Tissue Location | Expressed in neurons of the rolandic area of the brain (at protein level). Expressed in the brain |
Research Areas
Citations (0)
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Application Protocols
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$ 365.00
Cat# APR11013
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