Anti-F3 / Factor III / Tissue Factor / CD142 Reference Antibody (Chugai patent anti-TF)
Recombinant Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| FC, E, FTA |
---|---|
Primary Accession | P13726 |
Reactivity | Cynomolgus, Human |
Clonality | Monoclonal |
Isotype | IgG4SP |
Calculated MW | 150 KDa |
Target/Specificity | F3 / Factor III / Tissue Factor / CD142 |
---|---|
Endotoxin | < 0.001EU/ µg,determined by LAL method. |
Conjugation | Unconjugated |
Expression system | CHO Cell |
Format | Purified monoclonal antibody supplied in PBS, pH6.0, without preservative.This antibody is purified through a protein A column. |
Name | F3 |
---|---|
Function | Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. |
Cellular Location | [Isoform 1]: Membrane; Single-pass type I membrane protein |
Tissue Location | Lung, placenta and pancreas. |
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