Anti-TNFRSF17 / BCMA / CD269 Reference Antibody (belantamab)
Recombinant Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| FC, E, FTA |
---|---|
Primary Accession | Q02223 |
Reactivity | Cynomolgus, Human |
Clonality | Monoclonal |
Isotype | IgG1 |
Calculated MW | 146.06 KDa |
Target/Specificity | TNFRSF17 / BCMA / CD269 |
---|---|
Endotoxin | < 0.001EU/ µg,determined by LAL method. |
Conjugation | Unconjugated |
Expression system | CHO Cell |
Format | Purified monoclonal antibody supplied in PBS, pH6.0, without preservative.This antibody is purified through a protein A column. |
Name | TNFRSF17 |
---|---|
Synonyms | BCM, BCMA |
Function | Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK. |
Cellular Location | Cell membrane; Single-pass type III membrane protein. Endomembrane system; Single-pass type III membrane protein Note=Perinuclear Golgi-like structures |
Tissue Location | Expressed in mature B-cells, but not in T-cells or monocytes |

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