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Anti-RGMC / HFE2 Reference Antibody (DISC-0974)

Recombinant Antibody

     
  •  - Anti-RGMC / HFE2 Reference Antibody (DISC-0974) APR10593
    Anti-RGMC / HFE2 Reference Antibody (DISC-0974) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%
    detail
  •  - Anti-RGMC / HFE2 Reference Antibody (DISC-0974) APR10593
    The purity of Anti-RGMC / HFE2 Reference Antibody (DISC-0974)is more than 98.22 % ,determined by SEC-HPLC.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
FC, E, FTA
Primary Accession Q6ZVN8
Reactivity Rat, Cynomolgus, Human
Clonality Monoclonal
Isotype IgG1
Calculated MW 145.66 KDa
Additional Information
Target/Specificity RGMC / HFE2
Endotoxin < 0.001EU/ µg,determined by LAL method.
Conjugation Unconjugated
Expression system CHO Cell
Format Purified monoclonal antibody supplied in PBS, pH6.0, without preservative.This antibody is purified through a protein A column.
Protein Information
Name HJV (HGNC:4887)
Synonyms HFE2, RGMC
Function Acts as a bone morphogenetic protein (BMP) coreceptor (PubMed:18976966). Through enhancement of BMP signaling regulates hepcidin (HAMP) expression and regulates iron homeostasis (PubMed:18976966).
Cellular Location Cell membrane; Lipid-anchor, GPI- anchor. Note=Also released in the extracellular space
Tissue Location Adult and fetal liver, heart, and skeletal muscle.
Research Areas
Citations (0)
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$ 365.00
Cat# APR10593
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Availability: 4 weeks
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