Anti-L-selectin Reference Antibody (Aselizumab)
Recombinant Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| FC, E, FTA |
---|---|
Primary Accession | P14151 |
Reactivity | Human |
Clonality | Monoclonal |
Isotype | IgG2A |
Calculated MW | 145 KDa |
Target/Specificity | L-selectin |
---|---|
Endotoxin | < 0.001EU/ µg,determined by LAL method. |
Conjugation | Unconjugated |
Expression system | CHO Cell |
Format | Purified monoclonal antibody supplied in PBS, pH6.0, without preservative.This antibody is purified through a protein A column. |
Name | SELL |
---|---|
Synonyms | LNHR, LYAM1 |
Function | Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells (PubMed:12403782, PubMed:28011641, PubMed:28489325). Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia (PubMed:12403782, PubMed:28011641). |
Cellular Location | Cell membrane; Single-pass type I membrane protein |
Tissue Location | Expressed in B-cell lines and T-lymphocytes. |
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