Anti-IL-13Ra1 / CD213a1 Reference Antibody (MK-6105)
Recombinant Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| FC, E, FTA |
---|---|
Primary Accession | P78552 |
Reactivity | Cynomolgus, Human |
Clonality | Monoclonal |
Isotype | IgG2SA |
Calculated MW | 124.7 KDa |
Target/Specificity | IL-13Ra1 / CD213a1 |
---|---|
Endotoxin | < 0.001EU/ µg,determined by LAL method. |
Conjugation | Unconjugated |
Expression system | CHO Cell |
Format | Purified monoclonal antibody supplied in PBS, pH6.0, without preservative.This antibody is purified through a protein A column. |
Name | IL13RA1 |
---|---|
Synonyms | IL13R, IL13RA |
Function | Binds with low affinity to interleukin-13 (IL13). Together with IL4RA can form a functional receptor for IL13. Also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity. |
Cellular Location | Membrane; Single-pass type I membrane protein. |
Tissue Location | Ubiquitous. Highest levels in heart, liver, skeletal muscle and ovary; lowest levels in brain, lung and kidney Also found in B-cells, T-cells and endothelial cells |
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