Anti-CXCR5 / CD185 Reference Antibody (SAR113244)
Recombinant Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| FC, E, FTA |
---|---|
Primary Accession | P32302 |
Reactivity | Cynomolgus, Human |
Clonality | Monoclonal |
Isotype | IgG1 |
Calculated MW | 144.1 KDa |
Target/Specificity | CXCR5 / CD185 |
---|---|
Endotoxin | < 0.001EU/ µg,determined by LAL method. |
Conjugation | Unconjugated |
Expression system | CHO Cell |
Format | Purified monoclonal antibody supplied in PBS, pH6.0, without preservative.This antibody is purified through a protein A column. |
Name | CXCR5 |
---|---|
Synonyms | BLR1, MDR15 |
Function | Cytokine receptor that binds to B-lymphocyte chemoattractant (BLC). Involved in B-cell migration into B-cell follicles of spleen and Peyer patches but not into those of mesenteric or peripheral lymph nodes. May have a regulatory function in Burkitt lymphoma (BL) lymphomagenesis and/or B-cell differentiation. |
Cellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Location | Expression in mature B-cells and Burkitt lymphoma cells |
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