Anti-Tenascin C Reference Antibody (tenatumomab)
Recombinant Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| FC, E, FTA |
---|---|
Primary Accession | P24821 |
Reactivity | Human, Mouse |
Clonality | Monoclonal |
Isotype | IgG1 |
Calculated MW | 147.86 KDa |
Target/Specificity | Tenascin C |
---|---|
Endotoxin | < 0.001EU/ µg,determined by LAL method. |
Conjugation | Unconjugated |
Expression system | CHO Cell |
Format | Purified monoclonal antibody supplied in PBS, pH6.0, without preservative.This antibody is purified through a protein A column. |
Name | TNC |
---|---|
Synonyms | HXB |
Function | Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Promotes neurite outgrowth from cortical neurons grown on a monolayer of astrocytes. Ligand for integrins alpha-8/beta-1, alpha-9/beta-1, alpha-V/beta-3 and alpha- V/beta-6. In tumors, stimulates angiogenesis by elongation, migration and sprouting of endothelial cells (PubMed:19884327). |
Cellular Location | Secreted, extracellular space, extracellular matrix |
Tissue Location | Detected in fibroblasts (at protein level). |

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